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Assure RX, LLC is a personalized medicine company which specializes in pharmacogenetics and is dedicated to helping physicians determine the right drug at the right dose for individual patients suffering from medical conditions. The proprietary technology is based on pharmacogenetics - the study of the genetic factors that influence an individual's response to drug treatments - as well as evidence-based medicine and clinical pharmacology. The result is an easy to read report that can help doctors select the right drug, at the right dose, right now!
The company was founded in June 2006 to commercialize industry-leading personalized medicine technology. Cincinnati Children's Hospital Medical Center and Mayo Clinic are equity holders and technology collaborators.
Additional Investors:
-Ohio Tech Angels, Queen City Angels, Blue Chip Venture Company

Cervilenz™, Inc., headquartered near Cleveland, Ohio, is a manufacturer and marketer of a patented, FDA cleared device to predict preterm birth risk in pregnant women by accurately measuring cervical length. Preterm birth (delivery prior to 37 completed weeks of gestation) affects almost 13 percent of pregnancies annually in the United States, representing over 500,000 babies. It is a serious health problem, with increased risk for a variety of newborn complications and lifelong disabilities. Preterm birth is also the leading cause of infant death. Cervical length was established by the National Institutes of Health as a powerful predictor of preterm birth risk in a study utilizing a specialized ultrasound probe and technique. The Cervilenz device is a simple, low cost alternative that can be used by a healthcare professional to identify women who may benefit from progesterone therapy or further consultation by a specialist.
Additional investors:
-JumpStart Ventures, Arboretum Ventures, Chrysalis Ventures

Great Lakes Pharmaceuticals, Inc. is a clinical stage company focused on developing and commercializing products that prevent infections associated with indwelling catheters. Their first product, B-Lock™, is an anti-coagulant catheter lock solution that works against the bacterial and fungal microorganisms known to form biofilm structures in catheters. Biofilm related infections are the 8th leading cause of death in the U.S. Headquartered in Concord, OH with offices in San Diego, CA, Great Lakes Pharmaceuticals assembled team of experienced and distinguished scientists, clinicians and managers to assure development leading to commercialization of innovative, effective treatment of microbial infections in clinical and in outpatient settings.
Additional investors:
-JumpStart Ventures, Ohio Tech Angels

Juventas Therapeutics is a Cleveland Clinic spin-off company developing novel regenerative therapies for cardiovascular disease. Several studies have demonstrated that the company’s lead product, Stromal Derived Factor-1 (SDF-1) significantly increases cardiac function through promoting cell survival and revascularization after a heart attack. Juventas’ first generation SDF-1 platform is based on engineering cellular therapies currently in clinical trials to deliver SDF-1 to damaged heart tissue. Through a strategic partnership, Juventas anticipates advancing this platform to a Phase 1 Clinical Trial in 2008. Recent data also suggests that SDF-1 can also be delivered through non-cell based delivery methods providing a cheaper, logistically more manageable second-generation alternative to current cell therapy initiatives.
Additional investors:
-JumpStart Ventures, Fletcher Spaight, Early Stage Partners, Second Generation

Minimally Invasive Devices LLC (MID) is a medical device company that develops innovative products that facilitate and simplify Minimally Invasive Surgery. Surgery performed through less invasive access is the dominant growth opportunity in all surgical disciplines and is highly dependent upon the development of clever devices that enable difficult surgical maneuvers or allow them to be performed by more surgeons. MID will develop as its first two products Clear-Vu, a device to improve visualization during laparoscopic surgery, and Clear-Path, a device to facilitate the removal of kidney stones from the ureter. MID will continue to develop products that apply existing engineering technology to unmet needs in minimally invasive surgery through the principles of shape and access.
Additional investors:
-Ohio Tech Angels, Queen City Angels

Neuros Medical, a Cleveland, Ohio-based neurostimulation company, is focused on developing neurostimulation therapies for unmet needs to patients worldwide. The company’s platform technology, Nerve Block, provides patients with elimination of chronic pain and spasticity in a variety of applications including neuroma/residual limb pain with potential applications in cancer pain, diabetic neuropathy, cerebral palsy, multiple sclerosis, and stroke.
Additional investors:
-JumpStart Ventures, Ohio Tech Angels, Queen City Angels, Glengary Ventures

3X Systems provides Small and Mid-Sized Businesses (SMBs) with data management solutions that are designed to meet their unique business requirements. Our extensive experience with SMBs and their IT Providers has helped us design high value products that deliver a keen blend of technical capability, reliability, and simplicity.
The company's marquee product is the 3X Backup system. This solution delivers the benefits of a costly, online backup service in a portable, all-in-one device that can be purchased by the end customer or their IT services provider.
Additional investors:
-Ohio Tech Angels

Brand Thunder LLC, based in Columbus, was formed in April, 2007 to leverage the power of customization within the web browser and offer companies a compelling, patent-pending solution for creating a more persistent presence with their internet consumer. Brand Thunder has branded the browser and extended its functionality for some of the most recognizable brands in sports, music and the internet. The product extends brand’s marketing and communication efforts via applications using custom themes and skins. This brand extension enables Brand Thunder to “takeover” the user’s application, embedding multiple opportunities for revenue generation including search, sales, advertising and communication thus transforming a static application into a new advertising medium.
Additional Investors:
-Ohio Tech Angels

OnShift (formerly BSK Live) is a leading provider of integrated employee scheduling and communications technology to optimize labor utilization and control labor costs for employers with shift based workforces. BSKLive’s flagship product, StaffKnex, is an intuitive, web-based application that combines staff scheduling, work requirements, employee qualifications, business rules, and communications into a highly automated staff management system.
Additional investors:
-JumpStart Ventures

Citizen Groove is a digital portfolio solution that unites working musicians, music education, and music industry professionals. CG was built by college music majors turned professional musicians. Born out of a dorm room at Case Western Reserve University, the CG team has felt the needs and lived the transition of being full time music students to becoming professionals. The triple-threat of CG's understanding of the modern music market, application of innovative information technology, and business savvy is helping shape a brighter future for the music industry.. While professional development tools exist in other industries, this generation of musicians demands a higher performance network to showcase and catalog their craft. CitizenGroove plans to continue evolving with the needs of the greater music community, adding the newest web technology available.
StreamLink Software began as nonprofit executives saw a need for solutions to common management issues. When it became clear there was gap in quality, affordable products, StreamLink Software was formed to develop them. As StreamLink’s products have been developed, other leaders in sectors specific to nonprofits have joined in helping to create more effective tools. For example StreamLink Software is pleased to work with BoardSource to provide premier governance resources to nonprofit organizations through the StreamLink Board Management software. Also, the Foundation Center will provide the foundation center database as a part of the StreamLink Foundation Management Software.

Zebra Mobile specializes in helping newspapers develop and deploy a successful mobile strategy. Current clients include Philly.com, Startribune.com, MySA, SF Gate and the Columbus Dispatch.
Additional investors:
-Ohio Tech Angels, Plymouth Ventures

Absorbent Materials Company (ABS Materials) develops reactive glass products and nanosands for remediation or site-cleanups of volatile organic and related spills, plumes or gas discharge. ABS Materials are engineered to be fully reversable. Once having captured a spill, then can be recovered safely and spilled chemical compounds recovered. Founded in 2008, ABS Materials is creating commercial solutions extending from Dr. Edmiston's patented work in materials science and chemistry. ABS has completed a series of laboratory tests of a revolutionary class of reactive glass and engineered sands. These silica based materials are highly stable, hydrophobic and capable of capturing and recovering a range of hydrocarbons and pervasive solvents including TCEs, Organic Acids, BTEX, and PBEs. The first set of products are now in pilot testing for TCE remediation, BTEX recovery and Produced Water treatment for Oil and Gas production.
-JumpStart Ventures, Harris & Harris Group

Stanton Advanced Ceramics ("Stanton") develops, produces, and markets leading refractory technologies for global molten processing companies. The company’s patented FireSlayerTMceramic technology is a breakthrough advance that operates in the highest temperature, most severe thermal-cycle, and highest-corrosion refractory environments in existence (specifically, the metals, glass, coke, power generation, and concrete industries). The FireSlayer solution also saves companies money: compared to traditional ceramic materials, FireSlayer’s next generation ceramic material offers dramatic cost savings in the form of:
1) Significantly extended furnace life cycles
2) Reduced energy loss over the life of the furnace, and
3) Reduced furnace maintenance time and expense
Additonal investors:
-JumpStart Ventures

The Collaborent Group is a management company that designs, implements and operates collaborative business models for groups of organizations to control costs and improve operations.
Collaborent is ideal for groups of :
- Governments: municipalities, counties, school systems, libraries, special districts
- Universities
- Nonprofits
- Foundations
- Associations
Additional investors:
- Second Generation
Exacter, Inc., based in Columbus, is a diagnostic service provider that enables electric utilities to proactively avoid power outages. Distribution reliability is the top industry problem. Their service is marketed as Intelligence-Based Preventive Maintenance™ which is based upon mobile EXACTER™ surveying instrumentation units connected to a web portal via cellular communications. EXACTER units require no new rolling stock, new personnel, training, or capital expenditures for the customer. The utility maintenance dispatchers use the web portal to access data that locates failing equipment and its fault severity — Maintenance Merit™ — in a timely manner for the purpose of setting priorities for work crews to replace or repair failing equipment.
Additional investors:
-Ohio Tech Angels

I2C Technologies Ltd. headquartered in Uniontown, Ohio, and established as a Limited Liability Company in 2005 specializes in providing integrated and customized security and surveillance solutions. I2C has established its standard through its Total Solution Provider appproach utilizing IP video surveillance technology. IP cameras, also known as network cameras, are the future of video surveillance. The company's in-house programmers have created customizable software that reacts to the needs of the customer. I2C's surveillance systems boast some of the most robust technology in the industry today, and its cameras have the ability to react to trigger events (such as motion detectors), privde night vision footage and zoom into objects at an optical zoom rate of up to 35X. Furthermore, its surveillance systems are scalable for future needs.

VeriShot (formerly known as Charitee) is a leading provider of automated hole-in-one systems for golf courses. The VeriShot System uses a unique combination of solar powered and wireless technology so that the golf course can offer hole-in-one, closest-to-the-pin, and other contests to every golfer, every round resulting in additional excitement and increased volume and profits with no up-front or ongoing costs. After two years of pilot testing, VeriShot is rolling out systems across the United States.
Additional investors:
- JumpStart Ventures